On 2/27/2021 8:34 AM, Taxed and Spent wrote:
> On 2/27/2021 8:20 AM, Boron Elgar wrote:
>> On Sat, 27 Feb 2021 08:06:37 -0800, Taxed and Spent
>> > wrote:
>>
>>> On 2/27/2021 8:00 AM, Graham wrote:
>>>> On 2021-02-27 6:04 a.m., Snag wrote:
>>>>> On 2/26/2021 11:03 PM, Graham wrote:
>>>>>> On 2021-02-26 9:45 p.m., Snag wrote:
>>>>>>
>>>>>>>>
>>>>>>>
>>>>>>> Â*Â* So "it's for my own good" makes it OK . I wouldn't find it so
>>>>>>> annoying if this were truly the killer pandemic they claimed . Yes ,
>>>>>>> those with compromised health were hardest hit . But the fact remains
>>>>>>> that this thing has a fatality rate of .03-.05% , down in the weeds
>>>>>>> with the common cold and seasonal flu . Another factor that screams
>>>>>>> fraud and conspiracy is that hydroxychloroquine all at once is a
>>>>>>> viable treatment - after hundreds of thousands that could have been
>>>>>>> treated died while "they" were screaming no no no it'll kill you .
>>>>>>
>>>>>> Wow! So you know more than all those research scientists that did
>>>>>> careful studies and proved that what you write is a load of codswallop!
>>>>>> I'm surprised that Fauci hasn't contacted you with a job offer!
>>>>>>
>>>>>
>>>>> Â* I know that other trials has great results , and were quashed by the
>>>>> liberal media .
>>>>
>>>> Oh! Of course it's ALWAYS the liberal media.
>>>>
>>>> I know that there were doctors and researchers that were
>>>>> canceled for not spouting the party line .Â* You really should consider
>>>>> watching/reading something other than mainstream media .
>>>>
>>>> Liek FuxNews and QAnon?
>>>> FFS, take your head out of your arse!
>>>>
>>>
>>> "In this retrospective observational study of SARS-CoV-2 infected
>>> non-hospitalized patients hydroxychloroquine exposure was associated
>>> with a decreased rate of subsequent hospitalization. Additional
>>> exploration of hydroxychloroquine in this mildly symptomatic outpatient
>>> population is warranted."
>>>
>>> https://bmcinfectdis.biomedcentral.c...79-021-05773-w
>>
>> Open access published - for a fee. Try again.
>>
>
> no fee for me.
>


Our findings in the outpatient setting are in conflict with prior
observational studies conducted among hospitalized patients potentially
highlighting differences in effect based on the severity of disease
[27]. Following an initial infection by SARS-CoV-2 resulting in attack
of alveolar epithelial cells patients may develop a hyper-inflammatory
state characterized by activation of the innate immune system and
release of pro-inflammatory cytokines and chemokines. Patients who
experience this "cytokine storm progress rapidly to respiratory failure
and multi-organ failure [28,29,30,31]. In these hospitalized patients
the weak anti-inflammatory effects of hydroxychloroquine may be
insufficient to block the cytokine cascade, whereas more potent
immunosuppressive agents such as dexamethasone and tocilizumab have been
associated with beneficial effects [21, 32, 33].

By contrast, hydroxychloroquine has anti-viral effects, decreasing
SARS-CoV-2 viral load, and thus may be more suited in preventing the
significant tissue damage needed to incite the hyper-inflammatory state
[5, 34]. This would position hydroxychloroquine earlier in the clinical
course, at the time of early infection, prior to hospitalization need [35].