FoodBanter.com - View Single Post - HOW FATTY FOOD TRIGGERS DIABETES [Sanford-Burnham Medical Research Institute]

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Elmo wrote:
> On 16/08/2011 7:57 AM, Dr. Jai Maharaj wrote:
>> How fatty food triggers diabetes
>>
>> PTI
>> The Pioneer
>> Tuesday, August 16, 2011
>>
>> London - For the first time, scientists have discovered how fatty
>> food trips a genetic switch in the body that can trigger diabetes, a
>> finding they say could lead to a potential cure for the disease.
>>
>> In studies on mice and humans, a team of researchers at the Sanford-
>> Burnham Medical Research Institute in the US found that high-levels
>> of fat disrupted two key proteins that turn genes on and off.
>>
>> The "transcription factors" FOXA2 and HNF1A activate a pancreatic
>> enzyme that in healthy people prevents diabetes developing, the Daily
>> Mail reported.
>>
>> When the proteins stop working, the enzyme is shut down, which in
>> turn upsets the ability of insulin-secreting beta cells in the
>> pancreas to monitor blood sugar levels.
>>
>> Without this glucose sugar-sensing mechanism, blood sugar cannot be
>> regulated properly.
>>
>> The discovery, published in the journal Nature Medicine, helps
>> explain why Type 2 diabetes is so often linked to obesity and it
>> could also lead to a potential cure for the condition, the
>> researchers said.
>>
>> Study leader Dr Jamey Marth said, "Now that we know more fully how
>> states of over-nutrition can lead to Type 2 diabetes, we can see more
>> clearly how to intervene.
>>
>> "The identification of the molecular players in this pathway to
>> diabetes suggests new therapeutic targets and approaches towards
>> developing an effective preventative or perhaps curative treatment.
>> "This may be accomplished by beta cell gene therapy or by drugs that
>> interfere with this pathway in order to maintain normal beta cell
>> function."
>>
>> http://dailypioneer.com/361028/How-f...-diabetes.html
>>
>> More at:
>> http://www.dailypioneer.com
>>
>> Jai Maharaj, Jyotishi
>> Om Shanti
>>
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>
>
> More absolute crap from a clueless pretend medical ******.

yay