Mark Thorson wrote:

>> Here ya go. a nice little cite/site for you-
>> http://edis.ifas.ufl.edu/FS088
>
> That list is dangerously incomplete. It appears
> to have been compiled strictly from studies on
> interactions between specific drugs and grapefruit
> juice, and even with this restriction the list is
> incomplete. For example, colchicine is not listed,
> even though it has this interaction. Most drugs
> have not been studied for their interaction with
> grapefruit juice, and it would be an enormous
> mistake to assume that in the absence of data
> no interaction will occur.
>
> The mechanism by which grapefruit juice interacts
> with drugs is known -- it modulates P-gp.
> Therefore any drug known to be a P-gp substrate
> should be considered to have an interaction
> unless studies show it does not. Nearly all
> cancer chemotherapy drugs are known to be
> P-gp substrates. I don't know of any chemotherapy
> drug which is not a P-gp substrate, but I suppose
> they might exist.


Oddly, The American Cancer Society doesn't seem to feel any need to
advise cancer patients of this and advises that a varied diet as
tolerated is the goal to entice appetite and provide the best nutrition
to support treatment. Go figure.

Otherwise, the list is pretty darn complete from what I can tell.