Dan Abel wrote:
>
> I can't remember ever seeing any software computer use for numbers,
> whether binary, octal, decimal or hex, where the most significant digit
> wasn't first.

Standard UART serial I/O sends the LSB first,
followed by the other bits in increasing significance.

As I recall, the PDP-8 front panel labelled the bits
1 to 12 from left to right for some crazy reason, but
it used standard 12-bit binary integers with the LSB
on the right (bit 12) and the msb on the left (bit 1).